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integrin

   Also found in: Encyclopedia, Wikipedia 0.03 sec.
integrin /in·te·grin/ (in´tĕ-grin) any of a family of heterodimeric cell adhesion receptors, each consisting of an α and a β polypetide chain, that mediate cell-to-cell and cell-to–extracellular matrix interactions.
integrin
[integ′rin]
1 a protein that links the outside of a cell with its interior.
2 a heterodimeric molecule involved in cell-substate and cell-cell adhesion.


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Similarly, basic research on the significance of the integrin molecule led to the development of Tysabri.
The drug combats MS by binding to a protein called alpha-4 integrin on the surface of white blood cells, interfering with their entry into the brain.
Santa Cruz, CA, USA), or integrin [beta]3 (611141; BD Transduction Laboratories, Franklin Lakes, NJ, USA) or goat antibody against [beta]-actin (sc-1616; Santa Cruz Biotechnology, Inc.
 
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