Before that, a virtually identical Ultegra unit was already on the market with an indication for measuring platelet responses to IIB/IIIa inhibitors, such as abciximab and integrelin
Angioplasty patients at 100 Top hospitals were significantly more likely to be treated with stents and expensive new drugs like Reopro and Integrelin
than their counterparts at average hospitals, Chenoweth quotes still another Solucient data analysis.
Refining the treatment of women with unstable angina: a randomized, double-blind, comparative safety and efficacy evaluation of Integrelin
versus aspirin in the management of unstable angina.
a) Abciximab (c7E3) Chimeric compound RGD (b) sequence Kistrin Echistatin Cyclic peptides Integrelin
was studied in the setting of coronary angioplasty in IMPACT II, a large, multi-center Phase III clinical trial.
In the trial, Integrelin was tested in two different treatment arms.
Composite Efficacy Combined Endpoint Group 1 Group 2 Integrelin Placebo
In the comparison of patients who received Integrelin treatment to those who received placebo, the event rate of death and Q-wave myocardial infarction was 2.
The safety data related to Integrelin were very favorable.