insulinoma


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Related to insulinoma: hypoglycemia

insulinoma

 [in″su-lin-o´mah]
a tumor of the beta cells of the islets of Langerhans; although usually benign, it is one of the chief causes of hypoglycemia.

in·su·li·no·ma

(in'sŭ-li-nō'mă),
An islet cell adenoma that secretes insulin.

insulinoma

/in·su·li·no·ma/ (in″sdbobr-lin-o´mah) an islet cell tumor of the beta cells, usually benign, that secretes insulin and is one of the chief causes of hypoglycemia.

insulinoma

[in′səlinō′mə] pl. insulinomas, insulinomata
Etymology: L, insula + Gk, oma, tumor
a tumor, usually benign, of the insulin-secreting cells of the islets of Langerhans. Surgical resection of the tumor may be possible, thus limiting the development of hypoglycemia. Also called insuloma, islet cell adenoma. Compare islet cell tumor.
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Insulinoma

insulinoma

A well-differentiated pancreatic endocrine neoplasm associated with Whipple's triad:
(1) Symptoms and signs of hypoglycaemia;
(2) Concomitant plasma glucose level of 45 mg/dL or less; and
(3) Symptoms reverse with the administration of glucose. Amyloid is often found in insulinomas.

Prognosis
Insulinomas, especially if small, have an excellent prognosis.

insulinoma

Insuloma Oncology A pancreatic islet cell tumor, which is characterized by overproduction of insulin, resulting in hypoglycemia of sufficient severity to trigger a coma; insulinomas are typical of MEN I. See MEN I.

in·su·li·no·ma

(in'sŭ-li-nō'mă)
An islet cell adenoma that secretes insulin.
Synonym(s): insuloma.

insulinoma

A rare tumour of the INSULIN -producing cells of the PANCREAS. Insulinomas can produce large quantities of insulin and lead to the dangerous condition of HYPOGLYCAEMIA.

Insulinoma

Tumor that arises from the insulin-producing cells in the pancreas.

insulinoma

a tumor of the beta cells of the islets of Langerhans; although usually benign, it is one of the chief causes of hypoglycemia.
References in periodicals archive ?
Tell your doctor if you have been diagnosed with or have been suspected of having pheochromocytoma or an insulinoma.
The nodule was determined to be an insulinoma on histological analysis.
Animal insulinoma cell lines, including NIT-1 cells of mouse origin, are often used as in vitro models to study the functions of pancreatic [beta] cells.
These five islet autoantibodies are islet cell cytoplasmic autoantibodies (ICA); insulin autoantibodies (IAA); glutamic acid decarboxylase autoantibodies (GADA); insulinoma associated-2 autoantibodies (1A-2A); and zinc transporter-8 autoantibodies (ZnT8A).
The sensitivity is reduced if there is a lack of SSTR2 expression, as is seen in poorly differentiated NETs and insulinomas.
83 Anti-hyperglycemic effect and anti-oxidant properties demonstrated In vitro in Rat insulinoma cell lines (RINm5F) and isolated islets as well as in vivo in streptozotocin-treated male Wistar rats (Latha, M.
Nanoporous biocapsules for the encapsulation of insulinoma cells : biotransport and biocompatibility considerations.
My sister, Theresa Girard, was 46 with two children when she died in October 2006 from a rare cancer called insulinoma," said Ms.
Products of gamma-tocopherol reaction with NO2 and their formation in rat insulinoma (RINm5F) cells.
Insulinotropic hormone glucagon-like peptide-1 (7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma betaTC-1 cells.
The following types of hormone tumors were identified by these methods: papillary, follicular, and medullary carcinomas of the thyroid, gastrinoma, insulinoma, glucagonoma, merkel cell tumor, several carcinoids, small cell anaplastic carcinoma, prolactinoma, and growth hormone tumors.
Unless you can get the gene [that enables unrestricted cell growth] out of absolutely every cell," warns Furlanetto, "there's a possibility of developing insulinoma," a nonmalignant islet tumor that can cause dangerously low blood sugar.