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insulin-like growth factors

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insulin-like growth factors (IGF),
n a group of polypeptides responsible for the activity of growth hormones, similar in chemical structure to insulin.


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induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor.
Included among these growth factors, which are also produced by cancer cells, are insulin-like growth factors and gastrin-releasing peptide.
IMC-A12 is ImClone Systems' fully human IgG1monoclonal antibody that is designed to specifically target the human insulin-like growth factor type 1 receptor, thereby inhibiting certain ligands known as insulin-like growth factors I and II from binding to and activating the receptor.
 
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