insulin receptor substrate-2


Also found in: Acronyms.

insulin receptor substrate-2 (IRS-2),

intracellular molecules that are activated by insulin and mediate many of its effects.
References in periodicals archive ?
Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.
Obesity in insulin receptor substrate-2 deficient mice: disrupted control of arcuate nucleus neuropeptides.

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