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initiation codon |
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initiation codon [inish′ē·ā′shən kō′don] Etymology: L, initium, beginning, caudex, book the triplet of nucleotides, usually adenine-uracil-guanine (AUG) or, in some cases, guanine-uracil-guanine (GUG), that in eukaryotes and archea code for methionine and in bacteria code for formylmethionine, the first amino acids in all protein sequences. Also called initiator codon, start codon. initiation the beginning or introduction rites. In cell biology, the first stage of transcription. initiation codon the codon AUG which specifies the first amino acid, methionine, in protein synthesis. Called also initiator. initiation complex is formed at the initiation of protein synthesis and includes initiation factors, tRNA, mRNA and the ribosomal subunit. initiation factors (IF) a group of proteins that are required for initiation of protein synthesis to occur. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Located within VDR translation initiation site on exon II, the Fok1 polymorphism, a C[right arrow]T transition, creates an upstream initiation codon, resulting in a VDR molecule elongated by three amino acids (f) compared with those initiating translation from the downstream site (F) (Arai et al. A second in-frame initiation codon is at nucleotide position 93-95, in the same position as the start codon of the 10,200 strain. ATG offset" indicates the polymorphism location relative to the first base "A" of the ATG methionine initiation codon. |
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