initiation codon


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in·i·ti·a·tion co·don

a specific mRNA sequence (usually AUG, but sometimes GUG) that is the signal for the addition of fMet-tRNA and the beginning of translation.

initiation codon

[inish′ē·ā′shən kō′don]
Etymology: L, initium, beginning, caudex, book
the triplet of nucleotides, usually adenine-uracil-guanine (AUG) or, in some cases, guanine-uracil-guanine (GUG), that in eukaryotes and archea code for methionine and in bacteria code for formylmethionine, the first amino acids in all protein sequences. Also called initiator codon, start codon.

in·i·ti·a·tion co·don

(i-nish'ē-ā'shŭn kō'don)
A specific mRNA sequence (usually AUG, but sometimes GUG) that is the signal for the addition of fMet-tRNA and the beginning of translation.
Synonym(s): initiating codon.

initiation codon

a triplet of bases in mRNA with the sequence AUG (less commonly, GUG) that acts as a ‘start’ signal for TRANSLATION, specifying the first amino acid at the N-terminus of the POLYPEPTIDE CHAIN. see GENETIC CODE.

initiation

the beginning or introduction rites. In cell biology, the first stage of transcription.

initiation codon
the codon AUG which specifies the first amino acid, methionine, in protein synthesis. Called also initiator.
initiation complex
is formed at the initiation of protein synthesis and includes initiation factors, tRNA, mRNA and the ribosomal subunit.
initiation factors (IF)
a group of proteins that are required for initiation of protein synthesis to occur.
References in periodicals archive ?
An AUG initiation codon, not codon-anticodon complementarity, is required for the translation of unleadered mRNA in Eschenichia coli.
Synthesized ASOs designed to bind to the initiation codon and block translation have been effective against coxsackievirus B3 (Yang et al.
Even in the absence of a Shine-Dalgamo homology, for example, translational repression of the aph coding region of a mutant mRNA expressed in Streptomyces lividans is relieved when a short leader is adde d upstream of an extra 5'-terminal initiation codon [10].