Specific toxicological endpoints: oral & repeated-dose toxicity, inhalation toxicity
, sensitization, reprotox (mEST & hEST), carcinogenesis, nanotoxicology & bio-barriers
To determine the roles of CYP2A13/2F1 in NA-induced respiratory tract toxicity, the CYP2A13/2F1-humanized mice were compared to Cyp2abfgsnull mice for acute inhalation toxicity
of NA in vivo.
Our group has previously shown that flavorings used in e-cigarettes, may induce inhalation toxicity
," Goniewicz said by email.
This study suggests that various characteristics of e-cigarettes, including any flavorings, may induce inhalation toxicity
, and, therefore, caution should be used with these products until more comprehensive studies are performed.
The research project is part of a long-term study to investigate the chronic inhalation toxicity
Acute toxicity may be measured as oral, dermal and inhalation, acute inhalation toxicity
is measured by LC50.
2012) Ninety-day inhalation toxicity
study with a vapor grown carbon nanofiber in rats.
This antibacterial chemical found in hand sanitizers, toothpaste, garbage bags and clothing is linked to liver and inhalation toxicity
, can disrupt thyroid function and is toxic to aquatic life.
Chronic inhalation toxicity
and oncogenicity of methyl methacrylate in rats and hamsters.
Insmed also said that it will move ahead with the 9-month dog inhalation toxicity
study of ARIKACE as previously requested by FDA to determine if the findings of the rat inhalation carcinogenicity study are observed in a non-rodent model.
The finding is in contrast to previous literature suggesting that inhalation toxicity
was rare, said Dr.
For example, the evaluation of inhalation toxicity
cannot be conducted on fish.