Patients having haematological diseases such as idiopathic thrombocytopenia (ITP), haematological malignancy, myeloproliferative disorder, myelodysplasia, bone marrow infiltrative disorder
, immune disorder, and patients taking steroids or cancer chemotherapy were excluded from the study.
DISCUSSION: JLIS, described by Jessner & Kanof in 1953, (1) is known as a benign chronic T-cell infiltrative disorder
with lesions persisting for several months or years.
In view of all these features, working diagnosis of infiltrative disorder
was made and the patient was evaluated on that basis.
Diffuse and dense increases in reticulin with extensive intersections were seen and no evidence of parasite, granulomas or infiltrative disorders
2] Amyloidosis, either primary or secondary, is defined as a group of chronic infiltrative disorders
that have in common a beta-pleated sheet configuration visualized on X-ray diffraction, a fine fibrillar nonbranching appearance on electron microscopy, and an apple-green birefringence when examined under polarized light after staining with Congo red.
Low testosterone combined with low or normal LH/FSH levels suggests a secondary etiology of hypogonadism, which includes pituitary neoplasms, hyperprolactinemia, hemochromatosis infiltrative disorders
, genetic disorders of GnRH secretion, genetic disorders of gonadotropin secretion or action, genetic disorders of pituitary development, eating disorders, or use of anabolic steroids.
Thyroid antibody tests may help in equivocal situations, such as a normal radioiodine study in hyperthyroidism or evaluating the cause of hypothyroidism when infiltrative disorders
, Reidel's thyroiditis, or subacute granulomatous thyroiditis are suspected.
Given the laboratory findings, the negative surgical or radiation history to the neck, and the absence of any symptoms suggestive of infiltrative disorders
of the parathyroid glands, the diagnosis of idiopathic autoimmune hypoparathyroidism as a cause of her hypocalcemia was made.