infectious granuloma

granuloma /gran·u·lo·ma/ (gran″u-lo´mah) pl. granulomas, granulo´mata   an imprecise term for (1) any small nodular delimited aggregation of mononuclear inflammatory cells, or (2) such a collection of modified macrophages resembling epithelial cells, usually surrounded by a rim of lymphocytes.

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actinic granuloma  a round lesion with a raised border seen on skin chronically exposed to sunlight.

granuloma annula´re  a benign, self-limited disease consisting of round granulomas of the dermis in groups, with papules or nodules, mainly seen in young girls.

apical granuloma  modified granulation tissue containing elements of chronic inflammation, located adjacent to the root apex of a tooth with infected, necrotic pulp.

coccidioidal granuloma  secondary coccidioidomycosis.

eosinophilic granuloma 

1. Langerhans cell histiocytosis.

2. a disorder similar to eosinophilic gastroenteritis, with localized nodular or pedunculated lesions of the submucosa and muscle walls, especially of the pyloric area of the stomach, caused by infiltration of eosinophils, but without peripheral eosinophilia or allergic symptoms.

3. anisakiasis.

granuloma fissura´tum  a firm, red, fissured, fibrotic granuloma of the gum and buccal mucosa of an edentulous alveolar ridge between the ridge and cheek; caused by an ill-fitting denture.

infectious granuloma  one due to a specific microorganism, as tubercle bacilli.

granuloma inguina´le  a granulomatous venereal disease, usually seen in dark-skinned people, marked by purulent ulceration of the external genitals, caused by Calymmatobacterium granulomatis.

lethal midline granuloma  a rare lethal necrotizing granuloma that destroys the midface; it is nearly always preceded by longstanding nonspecific inflammation of the nose or nasal sinuses, with purulent, often bloody discharge.

lipoid granuloma  xanthoma.

lipophagic granuloma  granuloma with loss of subcutaneous fat.

midline granuloma  lethal midline g.

paracoccidioidal granuloma  paracoccidioidomycosis.

peripheral giant cell reparative granuloma  giant cell epulis.

pyogenic granuloma  a benign, solitary nodule resembling granulation tissue, found anywhere but often in the mouth, usually at the site of trauma as a tissue response to nonspecific infection.

reticulohistiocytic granuloma  a solitary reticulohistiocytoma that is not associated with systemic involvement.

sarcoid granuloma  the granuloma seen with sarcoidosis.

swimming pool granuloma  one that complicates injuries sustained in swimming pools, attributed to Mycobacterium balnei, often healing spontaneously over time.

trichophytic granuloma  tinea corporis, usually on the lower legs, due to Trichophyton infecting hairs at the site, with raised, circumscribed, boggy granulomas, scattered or in chains; lesions are slowly absorbed, or undergo necrosis, leaving scars.

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infectious granuloma

Etymology: L, inficere, to stain, granulum, little grain; Gk, oma, tumor

a lumpy lesion of granuloma tissue that may develop in diseases such as tuberculosis, syphilis, and actinomycosis.

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granuloma

a tumor-like mass or nodule of granulation tissue, with actively growing fibroblasts and capillary buds, consisting of a collection of modified macrophages resembling epithelial cells, surrounded by a rim of mononuclear cells, chiefly lymphocytes, and sometimes a center of giant multinucleate cells; it is due to a chronic inflammatory process associated with infectious disease or invasion by a foreign body.

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acropruritic granuloma

see acral lick dermatitis.

apical granuloma

modified granulation tissue containing elements of chronic inflammation located adjacent to the root apex of a tooth with infected necrotic pulp.

canine eosinophilic granuloma

see eosinophilic granuloma.

cholesterol granuloma

see cholesteatoma.

coccidioidal granuloma

the secondary, progressive, chronic (granulomatous) stage of coccidioidomycosis.

dental granuloma

one usually surrounded by a fibrous sac continuous with the periodontal ligament and attached to the root apex of a tooth.

enzootic nasal granuloma

see enzootic nasal granuloma.

equine dermal granuloma

see swamp cancer.

feline lick granuloma

see feline eosinophilic granuloma complex.

granuloma fissuratum

a firm, whitish, fissured, fibrotic granuloma of the gum and buccal mucosa, occurring on an edentulous alveolar ridge and between the ridge and the cheek.

foreign body granuloma

a localized histiocytic reaction to a foreign body in the tissue.

idiopathic sterile g's

occur in dogs and cats; the lesions are painless and may become ulcerated and secondarily infected. An immune-mediated cause is suspected and the lesions often respond to treatment with corticosteroids or other immunomodulating drugs. Sometimes lesions regress spontaneously.

infectious granuloma

infection by one of the systemic mycotic fungal agents which result in a granulomatous lesion in the skin.

intestinal eosinophilic granuloma

see angiostrongyluscostaricensis.

linear granuloma

well-delineated, elevated plaques with an eroded surface that occur in a linear pattern, usually on the caudal aspect of the hindleg(s) of cats. Pruritus is variable. Similar lesions may also occur in the oral cavity and on the lips. See also feline eosinophilic granuloma complex.

lipoid granuloma

a granuloma containing lipoid cells; xanthoma.

lipophagic granuloma

a granuloma attended by the loss of subcutaneous fat.

mycotic granuloma

see swamp cancer.

palisading granuloma

one characterized by the arrangement of histiocytes surrounding a focus of fibrin, foreign material, degenerating collagen.

paracoccidioidal granuloma

paracoccidioidomycosis.

peripheral giant cell reparative granuloma

a pedunculated or sessile lesion of the gingivae or alveolar ridge, apparently arising from the periodontium or mucoperiosteum, and usually due to trauma. It is uncommon in humans and animals. Called also reparative granuloma of the jaw.

pressure point granuloma

see pressure points.

pyogenic granuloma

a benign, solitary, nodule resembling granulation tissue, found anywhere on the body, commonly intraorally, usually at the site of trauma as a response of the tissues to a nonspecific infection.

reparative granuloma of the jaw

see peripheral giant cell reparative granuloma (above).

sperm granuloma

granuloma of the epididymis caused by leakage of spermatozoa from the efferent tubules or the epididymis into surrounding tissue. May be due to trauma, infection or to congenital defects in the duct system.

staphylococcal granuloma

a large mass containing small abscesses, found in the wall of the uterus of the sow. See also botryomycosis.

telangiectatic granuloma

a form characterized by numerous dilated blood vessels.

tuberculous granuloma

the lesion of tuberculosis and the prototype of granulomatous inflammation. It is composed of histiocytes and epithelioid cells surrounded by giant cells of the Langhans type, lymphocytes and fibroblasts. Bacteria are found in the cytoplasm of the epithelioid and giant cells.

ulcerative granuloma of swine

see ulcerative granuloma of swine.

venereal granuloma

see canine transmissible venereal tumor.