infantile spasms


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infantile spasms

a syndrome of severe myoclonus appearing in the first 18 months of life and associated with general cerebral deterioration. It is marked by severe flexion spasms of the head, neck, and trunk and extension of the arms and legs. Also called infantile massive spasms, jackknife seizures, jackknife spasms.

infantile spasms

An epilepsy-like syndrome affecting babies in the first year of life. The baby suddenly flexes the neck and trunk as if bowing (salaam attacks), the arms are thrown out and the legs are either extended sharply or drawn up. The spasm last for only a second or so but may be frequent. Possible causes include a congenital brain defect, brain injury at birth, prenatal infection, the effects of earlier meningitis or untreated PHENYLKETONURIA. In many cases no such cause is found. The outlook is often poor.
References in periodicals archive ?
In our study, 2 patients had seizure remission on follow-up consultation, and 2 had persistent infantile spasms.
Hussain, a pediatric epilepsy specialist and director of the Infantile Spasms Program at the University of California, Los Angeles.
In an effort to determine trends of treatment for infantile spasms at children's hospitals, including cost and initial diagnostic work-up, Dr.
We started recording her episodes and sent them to our doctors in the UK who confirmed in March that Grace has Infantile Spasms (West Syndrome)," said Richie.
INTRODUCTION: West syndrome is a rare epileptic disorder in infants, children and adults, characterized by triad of infantile spasm, path gnomic EEG pattern and developmental regression.
Infantile spasms (IS) is the most common catastrophic epilepsy of childhood.
KARACHI -- Infantile spasms are prevalent but are rare in Pakistani population.
Acthar Gel is an injectable drug that is approved for the treatment of exacerbations associated with multiple sclerosis, infantile spasms, opsoclonus myoclonus syndrome, and nephrotic syndrome.
generalised seizures including tonic, clonic, tonic-clonic, absence, myoclonic and atonic seizures and infantile spasms
I still remember reading his prognosis in Seizures and Epilepsy in Childhood: "Only ten percent of children with infantile spasms will have normal mental function; the vast majority will have moderate to severe mental retardation.
The only other FDA-approved treatment for infantile spasms is vigabatrin, sold under the brand name Sabril by Danish drugmaker H.