During each six-week treatment cycle, patients were given daily doses of 7MIU/square meter in the induction phase
and daily doses of 3.
The company is on track to report data from the induction phase
of this trial in the fourth quarter of 2008.
Eligible patients are permitted maintenance dosing with ipilimumab or placebo after the induction phase
has been completed.
Released preliminary data for the induction phase
of the company's phase III clinical trial in lupus nephritis.
VICTORIA, Canada/BASEL, Switzerland, June 27 /PRNewswire-FirstCall/ -- Aspreva Pharmaceuticals Corporation (NASDAQ: ASPV; TSX: ASV) and Roche today released preliminary results for a clinical trial comparing CellCept (oral mycophenolate mofetil, MMF) to intravenous cyclophosphamide (IVC), which is the current standard of care, for inducing treatment response in the induction phase
of patients suffering from lupus nephritis.
Preliminary results from the induction phase
of this trial are expected towards the end of June 2007.
Participants were given pegylated interferon alfa-2b at a dose of 6 microgram/kg/week for an eight week induction phase
followed by 3 microgram/kg/wk (maintenance phase), for total treatment duration of 5 years.
THESE are the kind of problems you can come across, especially in the Induction phase
Both phases of the trial met their primary endpoints, providing statistically significant improvements in clinical response in the induction phase
and clinical remission in the maintenance phase.
2] as an intravenous (IV) treatment on days 1-5 of a 21-day cycle during the induction phase
This may be used by some projects for young people in an induction phase
before they move on to the higher rate and by some projects which have lower attendance requirements; and
The trial evaluated the addition of either PKC412 (midostaurin) or placebo to daunorubicin/cytarabine in the induction phase
, followed by high-dose cytarabine in the consolidation phase; patients who achieved complete remission after consolidation chemotherapy continued treatment with PKC412 (midostaurin) or placebo as a single agent for up to one year.