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induction of remission

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induction of remission
Oncology The initial phase of a 3-step chemotherapeutic regimen used to treat acute leukemia; in ALL, prednisone and vincristine induce remission in 90% of children and 50% of adults, which ↑ to 80% by adding a third drug–eg, l-asparginase, daunorubicin or doxorubicin; in AML, therapeutic levels of these agents approach BM toxicity. See Consolidation chemotherapy, Maintenance chemotherapy.


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Patients who have extremely active disease can be treated intravenously to help with induction of remission.
3 mg/kg/wk) for remission maintenance in 114 patients with WG or MPA after the successful induction of remission with cyclophosphamide pulses, suggesting that both agents are similarly effective for the maintenance of remission.
Induction of remission by B lymphocyte depletion in eleven patients with refractory antineutrophil cytoplasmic antibody-associated vasculitis.
 
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