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In addition, the therapeutic regimens used in the induction of remission treatment step are similar throughout the world.
Conclusion: For initial induction of remission in melasma, modified Kligman's formula is recommended and subsequent long-term maintenance can be achieved with 2% kojic acid containing formulations.
A 2-year, randomized European trial showed that a top-down approach, combining early immunosuppression with infliximab (Remicade) and azathioprine (Imuran in Canada, Azasan in the United States) followed by azathioprine monotherapy and, if necessary, additional infliximab and corticosteroids, was more effective than step-up management for induction of remission and reduction of steroids in the short term (Lancet 2008;371:660-7).
The firm's ANDA product is a generic version of Salix Pharmaceuticals' Uceris, which is a glucocorticosteroid designed for induction of remission in patients with active, moderate to mild ulcerative colitis, a form of inflammatory bowel disease.
The product is a generic version of the company's Uceris, which is a glucocorticosteroid designed for the induction of remission in patients with active, mild to moderate ulcerative colitis, a form of inflammatory bowel disease.
The induction of remission treatment with cyclophosphamide pulse-therapy combined with steroids didn't have a favorable clinical outcome.
The two phases of treatment for inflammatory bowel disease are, firstly, induction of remission (getting the disease under control) and then therapies to maintain remission (keep control).
Furthermore, this review also examines in-depth the probiotic clinical trials published between 2007 and December 2010, providing new insights into the role of probiotics for inducing and maintaining remission of IBD, and highlighting some of the breakthroughs, especially regarding induction of remission for ulcerative colitis.
Nevertheless, because of the multiple adverse effects associated with their long term use, corticosteroids are recommended for the induction of remission only.
AAV treatment can be envisioned in two stages: induction of remission and maintenance.
A recent randomized controlled trial of 100 patients with antineutrophil cytoplasmic antibody-associated systemic vasculitis showed methotrexate may be able to replace cyclosporine for both induction of remission (methotrexate=89.
In terms of other biologic agents, the drug etanercept, in doses that are effective in rheumatoid arthritis, "is not effective in Crohn's disease," while the human monoclonal antibody natalizumab appears to have similar maintenance benefits to those of the anti-TNFs, "although there [are fewer] high-quality data to evaluate pertaining to induction of remission," the authors wrote.