induction failure

induction failure

A term of art referring to complete non-responsiveness to cancer therapy, which is characterised by increased size of malignant lesions or the appearance of new lesions.

induction failure

Oncology Complete nonresponsiveness to CA therapy, characterized by ↑ size of lesions or appearance of new lesions. Cf Complete remission, Minimal response, Partial remission.
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These results tell us that induction failure should no longer be considered an automatic indication for a transplant.
The definition of induction failure differed slightly among the clinical trials included in this analysis.
1 If labor is induced when the cervix is unfavorable it may increase the likelihood of induction failure, protracted and exhausting labors, and other complications.
Ten of the 41 patients in the "7+3" arm experienced primary induction failure and were subsequently treated with CPX-351.