inducible nitric oxide synthase


Also found in: Acronyms.

inducible nitric oxide synthase

the inducible isoform of nitric oxide synthase (NOS) found within phagocytic cells (Kupffer cells, macrophages), hepatocytes, and smooth muscle cells.
See also: nitric oxide synthase, nitric oxide.
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In Situ Expression of the Proinflammatory Cytokines Interleukin 1 (IL-1), Interferon [gamma] (IFN-[gamma]), and Tumor Necrosis Factor [alpha] (TNF-[alpha]), the Apoptosis Inducers Fas and Inducible Nitric Oxide Synthase (iNOS), and the Apoptosis Inhibitor Bcl-2, and the Presence of Apoptosis in Skin Biopsies From Patients With Endemic Pemphigus Foliaceus * Proinflammatory Cytokines: Exudate, No.
Activation of inducible nitric oxide synthase by Kagamjuaguiem in mouse peritoneal macrophages.
Inducible nitric oxide synthase was detectable by Western blotting in mouse cells, which produced increased amounts of NO (Figure 5).
Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides.
Ross, "Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene," Journal of Neuroscience, vol.
Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition.
Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa patients with active ulcerative colitis and Crohn's disease.
Probably the most pivotal enzymes involved in maintaining inflammation are the inducible enzymes; inducible nitric oxide synthase (iNOS/NOS2) and cyclooxygenase-2 (COX-2), which are responsible for the catalysis of NO and prostaglandin [E.
Nitric oxide (NO) has been shown to be an important factor in immunity, and play a pivotal role in modulating immune responses and inflammation, and it was synthesized from L-arginine by inducible nitric oxide synthase (iNOS) (Moilanen et al.
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.
The characteristics of the second phase, which lasted from 7 to 28 days, were elevated TNF[alpha] levels in BALF, expression of inducible nitric oxide synthase in BAL cells, and recruitment of mononuclear cells such as lymphocytes and macrophages into the airways.
Anti-human Bcl-2, Bcl-xl, Bax, caspase-3, and inducible nitric oxide synthase (iNOS) antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, Calif).