inducible nitric oxide synthase


Also found in: Acronyms.

inducible nitric oxide synthase

the inducible isoform of nitric oxide synthase (NOS) found within phagocytic cells (Kupffer cells, macrophages), hepatocytes, and smooth muscle cells.
See also: nitric oxide synthase, nitric oxide.
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References in periodicals archive ?
Varesio, A hypoxiaresponsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter, J.
There weren't any statistically significant differences in infiltrated inflammatory cells, density of inflammatory cells that stained with inducible nitric oxide synthase, or nitric oxide expression in gingiva between the patient and control groups (p>0.
Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin.
Inducible nitric oxide synthase is increased in routine lung epithelial cells by cytokine stimulmion.
Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.
today announced the initiation of a Phase IIa clinical trial of KD7040, an inducible nitric oxide synthase (iNOS) inhibitor formulated as a topical gel, for the treatment of postherpetic neuralgia (PHN).
PLC-induced dilatative adaptation, and growth was found associated with increased inducible nitric oxide synthase and reduced arterial vascular endothelial growth factor and intracellular adhesion molecule-1 expression.
Regulation of inducible nitric oxide synthase messenger RNA expression and nitric oxide production by lipopolysaccharide in vivo: the roles of macrophages, endogenous IFN-gamma and TNF receptor-1-mediated signalling.
12), (16) The investigators who found decreased NO levels state that NO metabolites originating from inducible nitric oxide synthase (iNOS) released from neutrophils could have resulted in the increased levels of NO found in some studies.
Increased inducible nitric oxide synthase expression and nitric oxide concentration in patients with aplastic anemia.