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indicator-dilution method

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indicator-dilution method,
a method for measuring blood volume. A known amount of a substance that dissolves freely in blood but does not leave the capillaries is injected intravenously. After a few minutes a sample of blood is withdrawn, and the volume of blood in the body is calculated from the concentration of the substance in the sample, the sample's volume, and the hematocrit.


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In 1987, the SNM Scientific Program Committee expanded its criteria to include all research that made use of the indicator-dilution method.
 
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