inactivation of complement


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inactivation of complement

Etymology: L, in + activus, complere, to complete
the loss of activity of the enzymatic proteins in blood, achieved by heating the serum to about 122° F (50° C). Inactivation of complement is a step in the process of complement fixation.

inactivation of complement

The destruction of complement proteins by pathogens (e.g., herpesviruses or measles virus); allergens (e.g., pollens); or in the laboratory, by heating serum to about 131°F (55°C) for a half hour. The destruction of complement by disease-causing organisms allows them to evade this aspect of the immune system.
See also: inactivation
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