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immunotoxin

   Also found in: Dictionary/thesaurus, Financial, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
immunotoxin /im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.
im·mu·no·tox·in (my-n-tksn, -my-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.

immunotoxin (IT)
[-tok′sin]
a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached.

immunotoxin
an antitoxin.


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United States Department of Health and Human Services (Washington, DC) has patented recombinant immunotoxin fusion proteins composed of the Fv domains of antibodies fused to bacterial or plant toxins.
These activated T cells are then eliminated with an immunotoxin against the cellular activation marker, CD25.
has assumed worldwide rights to develop and market LMB-9, a recombinant immunotoxin which was designed as a treatment for a wide variety of cancers.
 
 
 
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