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immunotoxin

   Also found in: Dictionary/thesaurus, Financial, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
immunotoxin /im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.
im·mu·no·tox·in (my-n-tksn, -my-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.
immunotoxin (IT)
[-tok′sin]
a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached.
immunotoxin
an antitoxin.


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Aflatoxins are immunotoxins that frequently contaminate staple foods in The Gambia and other parts of sub-Saharan Africa, resulting in high exposure throughout life.
Modification of immune function through exposure to dietary aflatoxin ... by Wild, Christopher P. / Environmental Health Perspectives
The company has four technologies: engineered mAbs, mAb-drug conjugates, single-chain immunotoxins and antibody-directed enzyme prodrug therapy (ADEPT).
SEATTLE GENETICS LICENSES PROACTA'S CELL-KILLING DRUGS by Worldwide Biotech
By fusing a cell-killing toxin to such an antibody, neuroscientists have created immunotoxins that seek out specific classes of nerve cells.
Kill the Messenger by TRAVIS, JOHN / Science News
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