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immunosuppressive |
Also found in: Dictionary/thesaurus, Encyclopedia, Hutchinson | 0.01 sec. |
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Immunosuppressive Any agent that suppresses the immune response of an individual. immunosuppressive [-səpres′iv] 1 adj, pertaining to a substance or procedure that lessens or prevents an immune response. 2 n, an immunosuppressive agent. The immunosuppressive drugs used most frequently to prevent allograft rejection are the interleukin 2 production inhibitors cycloSPORINE and tacrolimus, the cytotoxic purine antimetabolite azathioprine, the alkylating agent cyclophosphamide, and the adrenocorticosteroid predniSONE. Methotrexate, cytarabine, dactinomycin, and thioguanine are also potent immunosuppressive drugs. Monoclonal antibodies against the T cell receptor (muromonab-CD3) and interleukin 2 receptors (basiliximab and daclizumab) are also administered for immunosuppression. The use of some of these agents is being explored for the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. immunosuppressive 1. pertaining to or inducing immunosuppression. 2. an agent that induces immunosuppression. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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As with other treatments for lupus, there is a risk of relapse after the immunosuppressives have been stopped. Slow-acting antirheumatic drugs and immunosuppressives. Various biochemicals isolated from the urine of pregnant women have been put forth as immunosuppressives that could inhibit the mother's rejection response. |
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