This age-related reduction in immune system vigilance is called immunosenescence
Elderly persons have been postulated to have an increased susceptibility to-in addition to co-ocurring conditions-pneumococcal disease because of reduced splenic function (23), age-related changes in respiratory tract, immunosenescence
, and cellular senescence related to age-associated inflammation (23).
Deeks, HIV Infection, Inflammation, Immunosenescence
Singapore, Feb 13, 2014 - (ACN Newswire) - A*STAR's Singapore Immunology Network (SIgN) signed a three-year partnership with the National University of Singapore (NUS), National University Hospital (NUH) and Sanofi Pasteur to embark on a Phase IV clinical trial to understand age-related loss of immunity, known as immunosenescence
, in elderly.
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence
21) Most patients are thought to have age-related immunosenescence
, but a subset of patients have iatrogenic immunodeficiency.
Ageing is known to affect immune function, a phenomenon known as immunosenescence
, but how this happens is not clear," said study leader Laura Santambrogio, M.
We are becoming a nation of older people, and we had better focus our priorities, time, and resources on understanding immunosenescence
, designing vaccines against diseases that primarily afflict the elderly, improving vaccine immunogenicity and efficacy in the elderly, and funding vaccine delivery for the elderly.
Sample article topics include: state of the art therapeutic hypothermia; HIV infection, inflammation, immunosenescence
, and aging; and, mechanisms of endocrine resistance in breast cancer.
The research, published in FEMS Immunology & Medical Microbiology, reveals that daily consumption of probiotic cheese helps to tackle age-related changes in the immune system, researchers also known as immunosenescence
A team from Finlands Turku University concluded a daily portion of probiotic cheese can slow the degeneration of our bodies known as immunosenescence
, which makes it much harder to fight infections and respond to vaccinations.
Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence