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immunophenotypic analysis

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immunophenotypic analysis
[-fē′nōtip′ik]
a method for dividing lymphomas and leukemias into clonal subgroups on the basis of differences in cell surfaces and cytoplasmic antigens. The antigenic differences are detected with monoclonal antibodies and flow cytometry.


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In addition, B- and T-cell immunostains performed as part of the immunophenotypic analysis of the lymphoma cases were also used to assess for the presence of LELs as well as to confirm the presence of B-cell LELs.
Immunophenotypic analysis of the tumor was performed via a three-step immunoperoxidase method.
The notable peripheral blood monocytosis (2,000/ml) and bone marrow blast count of 10% were indicative of CMML, and flow cytometry immunophenotypic analysis and special staining were confirmatory.
 
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