The company said the patent includes claims covering plague antigens fused to its iBioModulator thermostable immunomodulator
, as well as vaccine compositions and a method for producing the antigen.
Study Selection: The inclusion criteria of articles were that the studies: (1) Randomized controlled trials which included patients with a diagnosis of IBD (established by standard clinical, radiographic, endoscopic, and histologic criteria); (2) exposed patients received immunomodulators
for maintenance (weight-appropriate doses of 6-mercaptopurine/azathioprine or within 3 months of stopping, 15 mg or more MTX per week or within 3 months of stopping; (3) exposed patients received nonimmunomodulators (no therapy, antibiotics only, mesalazine only, biological agent only such as infliximab, adalimumab, certolizumab or natalizumab or within 3 months of stopping one of these agents).
can take 3-4 months to reach peak clinical effect, and "the majority did well when infliximab was used as a bridge to immunomodulator
therapy," said Dr.
Treatment of patients with inflammatory bowel disease with the immunomodulators
azathioprine or 6-mercaptopurine is associated with about a fourfold increased risk of lymphoma, reported A.
All remained on immunomodulators
during and after the infusion treatment period while the investigators sought to determine infliximab's short-term efficacy, safety, and duration of response.
com/research/0851d3/the_immunomodulato) has announced the addition of the "The Immunomodulators
Market Outlook to 2016" report to their offering.
The IRX-2 immunomodulator
includes multiple cytokine components that work to activate different arms of the immune system.
NEW YORK -- IRX Therapeutics, a developer of novel immunomodulators
to treat cancer and viral diseases, today announced that it has established a strategic collaboration with Japan's National Cancer Research Center (NCRC) to evaluate next-generation peptide-based cancer vaccines.
The inflammation pathway offers a range of promising targets for the development of new immunomodulator
drugs used for treating atopic dermatitis recently received a black box safety warning from the FDA.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under a SPA and Fast Track, acts together with chemotherapy as a chemoprotectant and an immunomodulator
Data suggest that BG-12, an oral fumarate derivative, is an immunomodulator
with a novel mechanism of action with a combination of cytoprotective and anti-inflammatory properties.