immunomodulator


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immunomodulator

 [im″u-no-mod´u-lāt-er]
an agent that causes immunomodulation.

biologic response modifier

agent that modifies host responses to neoplasms by enhancing immune systems or reconstituting impaired immune mechanisms.
Synonym(s): immunomodulator

immunomodulator

/im·mu·no·mod·u·lat·or/ (-mod´u-la´ter) an agent that augments or diminishes immune responses.

immunomodulator

[-mod′yəlā′tər]
Etymology: L, immunis + modulus, little measure
a substance that alters the immune response by augmenting or reducing the ability of the immune system to produce antibodies or sensitized cells that recognize and react with the antigen that initiated their production. Immunomodulators include corticosteroids, cytotoxic agents, thymosin, and immunoglobulins. Some immunomodulators are naturally present in the body, and certain of these are available in pharmacological preparations. immunomodulation, n.

immunomodulator

agents that alter the immune response by suppression (immunosuppressive) or enhancement (immunostimulant).
References in periodicals archive ?
The company said the patent includes claims covering plague antigens fused to its iBioModulator thermostable immunomodulator, as well as vaccine compositions and a method for producing the antigen.
Study Selection: The inclusion criteria of articles were that the studies: (1) Randomized controlled trials which included patients with a diagnosis of IBD (established by standard clinical, radiographic, endoscopic, and histologic criteria); (2) exposed patients received immunomodulators for maintenance (weight-appropriate doses of 6-mercaptopurine/azathioprine or within 3 months of stopping, 15 mg or more MTX per week or within 3 months of stopping; (3) exposed patients received nonimmunomodulators (no therapy, antibiotics only, mesalazine only, biological agent only such as infliximab, adalimumab, certolizumab or natalizumab or within 3 months of stopping one of these agents).
Immunomodulators can take 3-4 months to reach peak clinical effect, and "the majority did well when infliximab was used as a bridge to immunomodulator therapy," said Dr.
Treatment of patients with inflammatory bowel disease with the immunomodulators azathioprine or 6-mercaptopurine is associated with about a fourfold increased risk of lymphoma, reported A.
All remained on immunomodulators during and after the infusion treatment period while the investigators sought to determine infliximab's short-term efficacy, safety, and duration of response.
com/research/0851d3/the_immunomodulato) has announced the addition of the "The Immunomodulators Market Outlook to 2016" report to their offering.
The IRX-2 immunomodulator includes multiple cytokine components that work to activate different arms of the immune system.
NEW YORK -- IRX Therapeutics, a developer of novel immunomodulators to treat cancer and viral diseases, today announced that it has established a strategic collaboration with Japan's National Cancer Research Center (NCRC) to evaluate next-generation peptide-based cancer vaccines.
The inflammation pathway offers a range of promising targets for the development of new immunomodulator drugs.
Immunomodulator drugs used for treating atopic dermatitis recently received a black box safety warning from the FDA.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under a SPA and Fast Track, acts together with chemotherapy as a chemoprotectant and an immunomodulator.
Data suggest that BG-12, an oral fumarate derivative, is an immunomodulator with a novel mechanism of action with a combination of cytoprotective and anti-inflammatory properties.