ICSI has been claimed as the primary choice of treatment in immunological infertility, as it overcomes any potential interference of ASA with sperm fertilizing ability.
Isolation and identification of sperm membrane antigens recognized by antisperm antibodies, and their possible role in immunological infertility disease.
There are several methods for the diagnosis of immunological infertility and detection of ASAs including sperm immobilization test, immunobead binding test (IBT), indirect immunofluorescence (IIF) and tissue engineering-based assay (9, 10).
If 40% or more of the spermatozoa were involved, the condition was considered as immunological infertility (17).
Bohring C and Krause W (2005): The role of antisperm antibodies during fertilization and for immunological infertility
Chem Immunol Allergy.
If screening for antibodies had not been done before entry into the programme, a mixed erythrocyte-spermatozoa antiglobulin test (MAR test) was done as a screening procedure to exclude male immunological infertility.
The sperm-cervical mucus contact test was conducted as a screening procedure in all the female patients to exclude a female immunological infertility factor.