immunohistochemistry


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im·mu·no·his·to·chem·is·try

(im'yū-nō-his'tō-kem'is-trē),
Demonstration of specific antigens in tissues by the use of markers that are either fluorescent dyes or enzymes such as horseradish peroxidase.

immunohistochemistry

,

IHC

The identification of antigens in tissues using antibodies that are linked to enzymes, fluorescent dyes, or radioactive labels. IHC is used to diagnose and track specific cellular anomalies, such as cancers, by identifying those antigens that are specifically found in affected cells.

im·mu·no·his·to·chem·is·try

(im'yū-nō-his'tō-kem'is-trē)
Demonstration of specific antigens in tissues by the use of markers that are either fluorescent dyes or enzymes.

immunohistochemistry,

n the demonstration of specific antigens in tissues by the use of markers that are either fluorescent dyes or enzymes, especially horseradish peroxidase. See also peroxidase, horseradish.
References in periodicals archive ?
NRASQ61R mutation-specific immunohistochemistry is highly specific for either NRASQ61R or KRASQ61R mutation in colorectal carcinoma [published online ahead of print February 9, 2016].
Applied Immunohistochemistry & Molecular Morphology: AIMM/official publication of the Society for Applied Immunohistochemistry 2014;22(4):241-252.
A number of different labels and chromagens, such as fluorescein isothiocyanate can be used, and therefore, it is possible to multiplex biomarker analysis in the same tissue section via double or even triple immunohistochemistry and immunofluorescence.
The molecular signature of lobular carcinoma of breast is a genetic alteration which results in loss of E Cadherin protein, which can be determined by immunohistochemistry.
After setting the diagnosis of B-ALL, having performed immunohistochemistry CD20 typing and ordering PCR for BCR-ABL fusion gene would affect the treatment options.
In contrast, immunohistochemistry uses specific antibodies to provide information on protein expression, including which cell types express the protein.
GenASIs Go-Path - Industry's Most Advanced Computer Aided Membrane and Nuclear Immunohistochemistry Imaging and Analysis Platform
Contract award notice: Provision of means for the production of immunohistochemistry slides, In immunofluorescence, In situ hybridization in the hcl anatomocytopathology departments (france-lyon: Medical equipments)
However, recently, the mutant protein-specific antibodies have been introduced into immunohistochemistry as an alternative, robust tool for the detection of specific mutations in cancer.
M2 PHARMA-October 6, 2014-Sigma-Aldrich to purchase Cell Marque to strengthen its immunohistochemistry business for undisclosed value
They have scientific expertise in peptide conjugations and in immunoassay, immunohistochemistry and immunocytochemistry kit development and formulation, as well as iodination of peptides.
Immunohistochemistry was negative for Sarcocystis falcatula and Neospora caninum and confirmed the protozoa as T gondii.