immunodominant

immunodominant

(ĭm″ū-nō-dŏm′ă-nĭnt)
Pert. to the ability of a specific antigen or epitope to induce a measurable or clinically meaningful immune response when other structurally related antigens do not. immunodominance, n.
References in periodicals archive ?
Collagen type II possesses one immunodominant T-lymphocyte epitope that binds to both variants of the predisposing HLA-DRB1* gene (HLA-DRB1*01 and HLA-DRB1*04).
VP1 is the most external and immunodominant of the picornavirus capsid proteins, and the VP1 sequence may be applied to classify enteroviruses and to analyze the phylogenetic relationships among human enteroviruses (32).
The assay utilizes well-defined antigens derived from HCV immunodominant proteins from the core region, the E2 hypervariable region (HVR), the NS3 helicase regions and the NS4A, NS4B, and NS5A regions as described previously.
Well-known surface and extra cellular antigens of pathogenic microorganisms among the immunodominant proteins of the infections microalgae Prototheca zopfii.
Immunodominant epitopes on the NS1 protein of MVE and KUN viruses serve as targets for a blocking ELISA to detect virus-specific antibodies in sentinel animal serum.
The envelope protein (E) is considered to be the immunodominant protein (Mandl, Guirakhoo, Holzmann, Heinz, & Kunz, 1989).
Microplates were precoated with HEV-specific synthetic antigens encoding for conservative and immunodominant derived from recombinant antigen of HEV.
Nexvax2 is an epitope-specific immuno-therapy that consists of three immunodominant peptides, designed to protect against gluten exposure.
Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
The antibodies (Abs) produced are generally targeted at immunodominant antigens that elicit a humoral response, notably MPB70 and MPB83 released in large amounts by M.