immunodominance

immunodominance

/im·mu·no·dom·i·nance/ (-dom´ĭ-nans) the degree to which a subunit of an antigenic determinant is involved in binding or reacting with antibody.

immunodominance

the property of an antigenic determinant that causes it to be responsible for the major immune response in a host.
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The feline antibody profiles were consistent with the known serologic immunodominance of these antigens in M.
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
Not every individual will generate cross-neutralizing antibodies since immunodominance is complex.
Other probiotic strain properties, such as immunodominance, adhesion on cell lines, and mucin and human biopsies are being studied.
The antigen-specific CD4+ response may not develop the dramatic immunodominance hierarchies that are well-known for CD8+ T cells and may be directed at many epitopes, more than are seen in the more-delimited CD8+ T-cell response.
MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I- restricted peptides recognized by antiviral CTL.
We did not observe a correlation between viral protein levels determined by SDS-PAGE (Figure 2, panel A) and immunodominance by Western blot analysis (Figure 2, panel B).