immunoablative

immunoablative

 [im″mu-no-ab´lah-tiv]
immunosuppressant with removal and destruction of a cell population, such as in the ablative step preceding bone marrow transplantation.

immunoablative

[im′mu-no·ab′lätiv]
immunosuppressant with removal and destruction of a cell population, such as in the ablative step preceding bone marrow transplantation.
References in periodicals archive ?
After receiving an autologous stem cell transplant (SCT), she experienced a relapse of disease and was enrolled in an experimental protocol of immunoablative chemotherapy, followed by hematopoietic SCT at the National Institutes of Health Clinical Center in Bethesda, Maryland (www.
The authors concluded that this immunoablative regimen of cyclophosphamide for patients with aggressive MS was safe, worthy of further study and may be an alternative to bone marrow transplantation.
A key to the success of this program is that patients receive a conditioning regimen that is immunoablative but not myeloablative.
The protocol involves preparing the patient with an immunoablative regimen, taking lymphocytes from a sibling treated with granulocyte-macrophage colony-stimulating factor, transferring the lymphocytes to the patient, and then giving the patient cyclosporine.
The use of G-CSF did not induce inflammatory activity in the central nervous system; CNS antibody production decreased after immunoablative therapy.