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immune surveillance |
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Some NHL in HIV-infected patients has been attributed to deficient immune surveillance of oncogenic herpesviruses, such as Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV-8), or perhaps to chronic antigenic stimulation and defective immune regulation. Since the viruses are hiding inside "self" cells, they could be impossible for immune surveillance cells to detect. One reason that cancer cells can survive and proliferate in the body is that they have found ways to escape normal immune surveillance. |
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