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immune hemolysis

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia, Wikipedia 0.01 sec.
hemolysis /he·mol·y·sis/ (he-mol´ĭ-sis) the liberation of hemoglobin, consisting of separation of the hemoglobin from the red cells and its appearance in the plasma.hemolyt´ic
immune hemolysis  lysis by complement of erythrocytes sensitized as a consequence of interaction with specific antibody to the erythrocytes.

immune hemolysis,
the destruction of red blood cells caused by the formation of specific antigen-antibody complexes in the presence of complement.

immune
1. being highly resistant to a disease because of the formation of humoral antibodies or the development of immunologically competent cells, or both, or as a result of some other mechanism, such as interferon activities in viral infections.
2. characterized by the development of antibodies or cellular immunity, or both, following exposure to antigen.
3. produced in response to antigen, such as immune serum globulin. The essential feature of antibody and cell-mediated immunity is that they are highly antigen specific.

immune adherence
the binding of antibody-antigen-complement complexes to complement receptors found on red blood cells.
immune complex
see antibody-antigen complex.
immune complex disease
disease induced by the deposition of or association with antigen-antibody-complement complexes in the microvasculature of tissues. Fixation of complement component C3 by the complexes initiates inflammation. See also serum sickness, hypersensitivity.
immune complex reaction
type III hypersensitivity (1).
immune deficiency disease
one in which animals have inadequate immune responses and so are more susceptible to infectious disease. The defect may be primary (inherited), or secondary (acquired) which usually develops after birth because of toxins or infectious agents. See also combined immune deficiency syndrome, hypogammaglobulinemia, agammaglobulinemia, inherited parakeratosis, chediak-higashi syndrome and canine granulocytopathy syndrome.
immune hemolysis
see immune-mediated hemolytic anemia (below).
immune interferon
immune modulator
immune reaction
immune response.
immune reaction fever
aseptic fever occurring in anaphylaxis, angioedema.
immune response
the specific response to substances interpreted by the body as not-self, the result being humoral and cellular immunity. The immune response depends on a functioning thymus and the conversion of stem cells to B and T lymphocytes. These B and T lymphocytes contribute to antibody production, cellular immunity and immunological memory. See also humoral immunity.
immune response (Ir) genes
see immune response genes.
immune surveillance
the detection by lymphocytes, especially T lymphocytes, of new antigens, particularly on tumor cells.
immune system
consists of the primary lymphoid organs (thymus and Bursa of Fabricius or its equivalent (bone marrow) in mammals) and secondary lymphoid organs (lymph nodes, spleen and other lymphoid tissue).
immune tolerance
see immunological tolerance.


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The mechanism of immune hemolysis observed in this patient involved the so-called drug absorption or hapten-specific mechanism, in common with most of the previous case reports.
If any findings in Phases 1 through 3 reveal a transfusion error or if transfusion-related hemolysis is strongly suspected, creatinine, BUN, bilirubin, and other testing may be done to support the diagnosis of immune hemolysis.
 
 
 
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