immotile cilia syndrome


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Related to immotile cilia syndrome: Reactive airway disease, ciliary dyskinesia

im·mo·tile cil·i·a syn·drome

[MIM*242650]
an inherited disorder characterized by recurrent sinopulmonary infections, reduced fertility in women, and sterility in men due to the inability of ciliated structures to beat effectively because of the absence of one or both dynein arms; autosomal recessive inheritance. Compare: Kartagener syndrome.

immotile cilia syndrome

[imō′til]
Etymology: L, im, motilis, movable, cilia, eyelashes; Gk, syn, together, dromos, course
a condition in which cilia, the hairlike processes of epithelial cells, fail to function normally. As a result, the patient has difficulty in filtering dust and other airborne debris from the respiratory system. See also Kartagener's syndrome.

immotile cilia syndrome

(1) Primary ciliary dyskinesia, see there.
(2) Kartagener syndrome, OMIM:244400.

immotile cilia syndrome

Kartagener syndrome An uncommon–1:20 000 AR disease of childhood onset due to defective or afunctional cilia in the respiratory tract, resulting in chronic sinusitis, defective mucociliary transport and bronchial clearance, bronchiectasia, chronic otitis media and incapacitating headaches, related to immotility of ependymal cilia in the walls of cerebral ventricles; other defects associated with IC include cardiovascular, renal and ocular defects, and absence of frontal sinuses Reproduction ♂ are infertile,12 of ♀ are impregnatable, the other12 sterile;12 have Kartagener's triad, ie chronic sinusitis, bronchiectasis and situs inversus totalis, the last of which may be due to an in utero defect with contrary beating cilia. See Cilia.

immotile cilia syndrome

congenital defect of ciliary movement recorded in dogs. See also primary ciliary dyskinesia, kartagener's syndrome.
References in periodicals archive ?
PCD also called immotile cilia syndrome is characterised by congenital abnormalities of ciliary function and structure [3, 4].