We can anticipate that vendors will introduce improved algorithms, detection systems, and reagents to improve blast, immature granulocyte
, and NRBC detection, which will further improve FPE.
, blast, and NRBC flags caused the most false-positive results with the optimized criteria (Table 6).
2 01 Immature Granulocyte
0 % 0-1 01 Immature Grans (Abs) 0.
Neutrophil, lymphocyte and eosinophil values can be expected to correlate well with results obtained from the analyser differential using the Sysmex XE-2100, however monocyte, basophil and immature granulocyte
numbers can be expected to correlate less well.
4) For example, the ADVIA 2120i displays immature granulocyte
flags by comparing parameters from the peroxidase and the basophil/lobularity chambers, whereas the XE 2100 uses the IMI channel to enumerate immature granulocytes
Among these, the immature granulocyte
(IG) parameter in peripheral blood has recently gained considerable interest.
Sysmex innovation as evidenced by the development of advanced clinical parameters such as Immature Platelet Fraction (IPF), Reticulocyte Hemoglobin (RET-He) and the Immature Granulocyte
(IG) count was also a key decision factor.
6,7) An upgraded software package (XE-IG Master, Sysmex) allows users to obtain an extended differential WBC count with the addition of an immature granulocyte
count, consisting of promyelocytes, myelocytes, and metamyelocytes, to the standard 5-part differential test.
Instruments are able to give percent and absolute counts of immature granulocyte
populations such as metamyelocytes, myelocytes, and promyelocytes.
today announced that the United States Food and Drug Administration (FDA) has cleared Sysmex's Immature Granulocyte
(IG) parameter and Reticulocyte Hemoglobin Equivalent (RET-He) parameter for use on the company's XT-Series(TM) Automated Hematology Analyzers for low to mid-volume laboratories, said John Kershaw, President, Sysmex America, Inc.
Features include advanced clinical parameters such as the immature granulocyte
(IG) and reticulocyte hemoglobin (RET-He) parameters.
What about other reportable FDA-cleared parameters, such as immature granulocyte
enumeration, or IG, and immature platelet fraction, or IPF?