In hematology, we will continue to automate and drive precise results, such as with our expanded CBC including immature granulocyte
(IG) analysis, immature platelet fraction (IPF), and reticulocyte hemoglobin (RET-He).
, blast, and NRBC flags caused the most false-positive results with the optimized criteria (Table 6).
2 01 Immature Granulocyte
0 % 0-1 01 Immature Grans (Abs) 0.
Neutrophil, lymphocyte and eosinophil values can be expected to correlate well with results obtained from the analyser differential using the Sysmex XE-2100, however monocyte, basophil and immature granulocyte
numbers can be expected to correlate less well.
4) For example, the ADVIA 2120i displays immature granulocyte
flags by comparing parameters from the peroxidase and the basophil/lobularity chambers, whereas the XE 2100 uses the IMI channel to enumerate immature granulocytes
Among these, the immature granulocyte
(IG) parameter in peripheral blood has recently gained considerable interest.
We can anticipate that vendors will introduce improved algorithms, detection systems, and reagents to improve blast, immature granulocyte
, and NRBC detection, which will further improve FPE.
6,7) An upgraded software package (XE-IG Master, Sysmex) allows users to obtain an extended differential WBC count with the addition of an immature granulocyte
count, consisting of promyelocytes, myelocytes, and metamyelocytes, to the standard 5-part differential test.
Instruments are able to give percent and absolute counts of immature granulocyte
populations such as metamyelocytes, myelocytes, and promyelocytes.
Features include advanced clinical parameters such as the immature granulocyte
(IG) and reticulocyte hemoglobin (RET-He) parameters.
What about other reportable FDA-cleared parameters, such as immature granulocyte
enumeration, or IG, and immature platelet fraction, or IPF?
Currently, there is a move to have the "left-shift" cells grouped into an immature granulocyte