imipramine


Also found in: Dictionary, Thesaurus, Wikipedia.
Related to imipramine: fluoxetine

imipramine

 [ĭ-mip´rah-mēn]
a tricyclic antidepressant of the dibenzazepine group, used also in the treatment of childhood enuresis, panic disorder, chronic pain, attention-deficit/hyperactivity disorder, cataplexy associated with narcolepsy, urinary incontinence, and bulimia nervosa. Administered orally or intramuscularly as the hydrochloride salt and orally as the pamoate salt.

imipramine

/imip·ra·mine/ (ĭ-mip´rah-mēn) a tricyclic antidepressant of the dibenzazepine class, used as i. hydrochloride or i. pamoate.

imipramine

(ĭ-mĭp′rə-mēn′)
n.
A tricyclic drug, C19H24N2, used in the form of its salts to treat depression and enuresis.

imipramine

Neuropharmacology A dibenzazepine class tricyclic antidepressant used for depression, enuresis Adverse effects Insomnia, numbness, tingling, tremors, seizures, dry mouth, blurred vision

imipramine

A widely used tricyclic antidepressant drug. A brand name is Tofranil.

imipramine

a tricyclic antidepressant used in the treatment of behavior disorders and urinary incontinence in dogs.
References in periodicals archive ?
The lower limit of the therapeutic range in patients treated with imipramine is a combined plasma concentration of imipramine and desipramine of 180 [micro]g/L; the upper limit is in the range of 350 [micro]g/L.
Furthermore, the reanalysis uncovered "clinically significant" increases in psychiatric harms in the paroxetine group and cardiovascular effects in the imipramine group, said Dr.
It has been demonstrated to be as effective as fluoxetine or imipramine with a similar or better tolerance profile.
In past studies in which the imipramine toxicity rate on liver was done, it was stated that imipramine causes damage to the liver, and in severe conditions requires transplant [23].
Sage and colleagues shortlisted six antidepressants, out of which imipramine and promethazine emerged as successful candidates for further study based on the results of experiments using SCLC cell lines and mice bearing human SCLC tumors.
The tricyclic antidepressant imipramine (20 mg/kg) (F) was used as positive control.
The most commonly used one is imipramine, but other drugs including amitriptyline and desipramine are also efficient.
SAMe consistently performs as well as or better than older-generation antidepressants such as imipramine and desipramine, drugs which are highly effective but have an unfavorable safety profile.
A small trial conducted in 1978 showed improvement in the Hamilton Depression Rating Scale score for 39 oncology patients taking imipramine (3).
Sertraline and clozapine belong to antidepressant and antipsychotic drugs respectively, while imipramine is a tricyclic antidepressant.
Antidepressants, such as imipramine and Prozac, reverse the effects of bullying on both social interactions and gene activity, but only when the mice keep taking the drug.