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imipenem |
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imipenem /im·i·pen·em/ (im″ĭ-pen´em) a β with a broad spectrum of activity against both gram-positive and gram-negative organisms.
imipenem [im″ĭ-pen´em] a β-lactam antibiotic with a broad spectrum of activity against gram-positive and gram-negative organisms. Because it is metabolized in the kidneys, it is administered with the enzyme inhibitor cilastatin in order to decrease the amount of it that is degraded by an enzyme in the kidneys.
imipenem one of the carbapenem group of antibiotics which are β-lactamase resistant. It has a very wide spectrum, but is inactivated by renal tubular enzymes and is given in association with cilastatin, which inhibits renal metabolism. Called also thienamycin. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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