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imine

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imine (ĭ-mēn´) an organic compound containing an imino group; in a substituted imine, a nonacyl group replaces the imino hydrogen.
im·ine (mn, -n, -mn)
n.
A compound derived from ammonia and containing the bivalent NH group combined with a bivalent nonacid group.


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Among them were 1,4-benzoquinone (a mutagen) and N-acetyl-p-benzoquinone imine (a hepatotoxicant also produced during acetaminophen metabolism that is responsible for overdose deaths).
Isolation and analysis of products demonstrated that 40-70% of the imine or diimine was reduced to the corresponding PPD, while 2050% was isolated as the alkylated product.
The hypothesized mechanism of carcinogenicity is bioactivation of these herbicides through several steps, ultimately leading to the formation of a DNA-reactive metabolite (Figure 2), 2-methyl-6-ethylbenzoquinone imine (MEBQI) for acetochlor and metolachlor and 2,6-diethylbenzoquinone imine (DEBQI) for alachlor and butachlor.
 
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