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imatinib |
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imatinib /im·at·i·nib/ (ĭ-mă´tĭ-nib″) an antineoplastic used as the mesylate salt in the treatment of chronic myeloid leukemia, inhibiting an abnormal enzyme form constitutively produced in the disease. imatinib [imă′tĭnib′] an inhibitor acting specifically on an abnormal enzyme form that is created by the Philadelphia chromosome abnormality and present in chronic myeloid leukemia. It is administered orally as the mesylate salt in the treatment of chronic myeloid leukemia during blast crisis, accelerated phase, or chronic phase after failure of interferon-alpha therapy. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Since its introduction a few years ago, the cancer drug imatinib has given patients with chronic myelogenous leukemia an unprecedented chance at long-term survival. ChemGenex is currently conducting a Phase 2/3 registration-directed study evaluating the use of Ceflatonin([R]) in CML patients who have the T315I Bcr-Abl point mutation that is associated with resistance to imatinib and other tyrosine kinase inhibitors. In the past few years, the breakthrough drug imatinib has changed chronic myeloid leukemia from a death sentence to a treatable disease. |
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