iduronate

i·dur·o·nate

(ī-dūr'ō-nāt),
The salt or ester of iduronic acid.
References in periodicals archive ?
MPS I and MPS II are caused by mutations in the genes encoding alpha-L-iduronidase (IDUA) and iduronate 2-sulfatase (IDS) enzymes, respectively.
In family M, the mother was heterozygous for an iduronate 2-sulfatase (IDS/IDS2) gene rearrangement.
8] Human genes: CYP21A2, cytochrome P450 family 21 subfamily A member 2; IDS, iduronate 2-sulfatase; IDSP1 or IDS2, iduronate 2-sulfatase pseudogene 1; CYP21A1P, cytochrome P450 family 21 subfamily A member 1, pseudogene; F8, coagulation factor VIII; EVC2, EvC ciliary complex subunit 2; EVC, EvC ciliary complex subunit 1; HBB, hemoglobin subunit beta; F9, coagulation factor IX.
Laboratory scale production of the human recombinant iduronate 2 sulfate sulfatase-like from Pichia pastoris.
Children with the disease, also known as MPS Type II, are missing an enzyme called iduronate sulphate sulphatase.
Colin lacks an enzyme known as iduronate sulphatas, which means his body cannot break sugar down properly.
MPS I and MPS II are caused by mutations in the genes encoding alpha-L-iduronidase and iduronate 2-sulfatase enzymes, respectively.
Hunter disease is caused by deficiency of iduronate 2-sulfatase (IDS) (EC 3.
A description of the method used for the synthesis of the iduronate 2-sulfatase substrate (IDS-S) from commercially available heparin and the iduronate 2-sulfatase internal standard (IDS-IS), along with structures of the materials, is provided in the Data Supplement that accompanies the online version of this technical brief at http://www.
Iduronate sulfatase activity was expressed as nanomoles of substrate hydrolyzed per liter of blood per hour.