idoxuridine /idox·ur·i·dine/ (i″doks-u´rĭ-dēn) an analogue of pyrimidine that inhibits viral DNA synthesis; used as an antiviral agent in the treatment of herpes simplex keratitis.
idoxuridine
idoxuridine
i·dox·u·ri·dine (  d ks-y r  -d n)n. Abbr. IDU A pyrimidine analog that produces both antiviral and anticancer effects by interfering with DNA synthesis and is used locally for the treatment of keratitis from herpes simplex or vaccinia. |
idoxuridine
[ī′doksyoo͡r′ədēn]
an ophthalmic antiviral.
indication It is prescribed for the treatment of herpes simplex keratitis.
contraindications Deep ulceration of the cornea or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are visual disturbances and eye discomfort.
idoxuridine
a pyrimidine analog that prevents replication of DNA viruses; used topically in infection by herpesviruses.
antiviral agents
Substances which inhibit the growth of a virus (e.g. herpes) by inhibiting DNA or RNA synthesis. Common agents include aciclovir (acyclovir), idoxuridine, ganciclovir, trifluoridine (trifluorothymidine) and vidarabine. See herpetic keratitis; virus.
idoxuridine
Virology A topical antiviral available in an ophthalmic solution for treating herpetic and other viral infections of the cornea
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