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idiopathic pulmonary hypertension |
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idiopathic pulmonary hypertension Primary pulmonary hypertension, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Genetic studies of familial idiopathic pulmonary hypertension (PH) revealed that a germline mutation in one copy of bone morphogenetic protein (BMP) receptor II occurs in about 80% of patients with familial idiopathic PH (1, 2). Older studies have estimated the incidence of idiopathic pulmonary hypertension to be one to two cases per million, with autopsy studies showing a prevalence of 1,300 per million. Such speculation is justified on the basis of the evidence for overproduction of this compound in adult humans with idiopathic pulmonary hypertension (20). |
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