idiopathic pulmonary fibrosis

fibrosis /fi·bro·sis/ (fi-bro´sis) formation of fibrous tissue.fibrot´ic

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congenital hepatic fibrosis  a developmental disorder of the liver marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.

cystic fibrosis , cystic fibrosis of the pancreas a generalized hereditary disorder of infants, children, and young adults, with widespread dysfunction of exocrine glands, signs of chronic pulmonary disease, obstruction of pancreatic ducts by eosinophilic concretions and consequent pancreatic enzyme deficiency, and other symptoms.

endomyocardial fibrosis  idiopathic myocardiopathy seen endemically in parts of Africa and less often in other areas, characterized by cardiomegaly, thickening of the endocardium with dense, white fibrous tissue that often extends to involve the inner third or half of the myocardium, and congestive heart failure.

idiopathic pulmonary fibrosis  chronic inflammation and progessive fibrosis of the pulmonary alveolar walls, with progressive dyspnea and potentially fatal lack of oxygen or right heart failure. The acute form is called Hamman-Rich syndrome.

mediastinal fibrosis  fibrous mediastinitis; development of white, hard fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels.

nodular subepidermal fibrosis 

1. benign fibrous histiocytoma.

2. a type of benign fibrous histiocytoma marked by subepidermal formation of fibrous nodules as a result of productive inflammation.

pleural fibrosis  fibrosis of the visceral pleura so that part or all of a lung becomes covered with a thick layer of nonexpansible fibrous tissue; fibrothorax is a more extensive form.

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idiopathic pulmonary fibrosis

Etymology: Gk, idios, own, pathos, disease; L, pulmoneous, the lungs, fibra, fiber

a disorder of unknown cause characterized by fibrosis of the lungs. It may follow an earlier inflammation or disease, such as tuberculosis or pneumoconiosis.

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fibrosis [fi-bro´sis]

formation of fibrous tissue; see also fibroid degeneration. adj., adj fibrot´ic.

congenital hepatic fibrosis a developmental disorder of the liver, marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.

cystic fibrosis (cystic fibrosis of pancreas) see cystic fibrosis.

diffuse idiopathic interstitial fibrosis (diffuse interstitial pulmonary fibrosis) idiopathic pulmonary fibrosis.

endomyocardial fibrosis an idiopathic type of myocardiopathy that is endemic in various parts of Africa and rarely in other areas, characterized by cardiomegaly, marked thickening of the endocardium with dense white fibrous tissue that may extend to involve the inner myocardium, and by congestive heart failure.

idiopathic pulmonary fibrosis chronic inflammatory progressive fibrosis of the pulmonary alveolar walls, with steadily progressive dyspnea, resulting in death from oxygen lack or right heart failure. Most cases are of unknown origin, although some are thought to result from pneumoconiosis, hypersensitivity pneumonitis, scleroderma, and other diseases.

mediastinal fibrosis development of hard white fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels; called also fibrosing or fibrous mediastinitis.

periureteral fibrosis retroperitoneal fibrosis.

pleural fibrosis fibrosis of the visceral pleura so that part or all of a lung becomes covered with a plaque or a thick layer of nonexpansible fibrous tissue. The more extensive form is called fibrothorax.

postfibrinous fibrosis that occurring in tissues in which fibrin has been deposited.

proliferative fibrosis that in which the fibrous elements continue to proliferate after the original causative factor has ceased to operate.

pulmonary fibrosis idiopathic pulmonary fibrosis.

retroperitoneal fibrosis deposition of fibrous tissue in the retroperitoneal space, producing vague abdominal discomfort, and often causing blockage of the ureters, with resultant hydronephrosis and impaired renal function, which may result in renal failure. Called also Ormond disease.

fibrosis u´teri a morbid condition characterized by overgrowth of the smooth muscle and increase in the collagenous fibrous tissue of the uterus, producing a thickened, coarse, tough myometrium.

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idiopathic pulmonary fibrosis

Idiopathic interstitial fibrosis of lung Pulmonology An idiopathic condition characterized by scarring and fibrosis of alveolar septae more common in middle-aged men, possibly related to collagen vascular disease, with positive 'rheumatoid' serology Clinical Aggressive–rapid onset of dyspnea, orthopnea, hemoptysis, cyanosis, clubbing of fingers and toes, pulmonary HTN, bibasilar rales, non-productive cough, death in 3-6 yrs Imaging Diffuse reticulonodular infiltrates. See Diffuse interstitial fibrosis, Lymphoid interstitial fibrosis, Usual interstitial fibrosis.