hypothalamic-pituitary axis


Also found in: Acronyms.

hypothalamic-pituitary axis

Endocrinology Any feedback system that coordinates the activity of major peptide hormones; the hypothalamus synthesizes releasing hormones, which act on the pituitary, which evokes end-organ responses
Hypothalamic-pituitary–HP 'axes'
• HP adrenocortical-ACTH-adrenal gland axis
• HP-FSH/LH-gonadal axis
• HP-TSH-thyroid gland axis
• HP-growth hormone-somatotroph axis
• HP-hypothalamic-lactotroph-breast axis 
References in periodicals archive ?
Exposure to uncontrollable stress has specific neurochemical and neuroendocrine consequences that include central catecholamine depletion, decreased gamma-amino butyric acid (GABA) release, and altered hypothalamic-pituitary axis function.
These include the production of photodegradation products of vitamin D that appear to modulate the action of vitamin D; the synthesis of corticotropin-releasing hormone (an immunomodulator) by the skin; and possible direct stimulation of the hypothalamic-pituitary axis through the retina.
Key words: gonadotropin-releasing hormone, hypothalamic-pituitary axis, lead acetate.
Littley MD, Shalet SM, Beardwell CG: Radiation and the hypothalamic-pituitary axis.
Altered reactivity of the hypothalamic-pituitary axis in the primary fibromyalgia syndrome.
Seventh, the adrenal gland cannot be understood except through its inter-relationship with the hypothalamic-pituitary axis (HPA), gonadal output, insulin metabolism, energy economy of the body, the oxygen-driven bioenergetics, and chronic stress.
This pattern may be due to the mode of action of Androxal(TM), which appears to be mediated through effects on the hypothalamic-pituitary axis.

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