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hyposalivation

   Also found in: Wikipedia 0.04 sec.
hyposalivation /hy·po·sal·i·va·tion/ (hi″po-sal″ĭ-va´shun) hypoptyalism.
hy·po·sal·i·va·tion (hp-sl-vshn)
n.
Abnormally reduced salivation. Also called hypoptyalism.

hyposalivation
[-sal′ivā′shən]
Etymology: Gk, hypo + L, saliva, spittle
a decreased flow of saliva associated with dehydration, radiation therapy of the salivary gland regions, anxiety, menopause, the use of drugs such as atropine and antihistamines, vitamin deficiency, inflammation or infection of the salivary glands, or various syndromes, such as Plummer-Vinson syndrome. Also called asialorrhea. See also xerostomia.

hyposalivation (hī´pōsal´ivā´shn),
n a decreased flow of saliva. It may be associated with dehydration, radiation therapy of the salivary gland regions, anxiety, the use of drugs such as atropine and antihistamines, vitamin deficiency, various forms of parotitis, and various syndromes (Sjögren's, Riley-Day, Plummer-Vinson, and Heerfordt's disease). See also asialorrhea.

hyposalivation
hypoptyalism.


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If salivary flow is adequate, the oral cavity will appear wet; if hyposalivation is present, the oral cavity will become dry.
Over 400 drugs have been identified as causing hyposalivation and xerostomia (dry mouth) (Sreebny & Valdini, 1987).
Scarantino, lead investigator of the RTOG study on Salagen Tablets, in his presentation entitled: "A Phase 3 study on the concurrent use of pilocarpine to reduce hyposalivation and mucositis associated with radiation therapy in head an neck cancer patients - final results of RTOG 97-09.
 
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