hy·po·my·e·li·na·tion, hypomyelinogenesis (hī'pō-mī'ĕ-lin-ā'shun, -ō-jen'ĕ-sis),
Defective formation of myelin in the spinal cord, brain, or peripheral nerves; responsible for various neurologic disease labeled disorders.
hy·po·my·e·li·na·tion,hypomyelinogenesis (hī'pō-mī'ĕ-lin-ā'shun, -ō-jen'ĕ-sis)
Defective formation of myelin in the spinal cord and brain; the basis for a number of demyelinating diseases.
inadequate synthesis of myelin; includes failure of formation of myelin, plus incomplete and delayed myelination of axons. It occurs in several species and may be caused by simple nutritional deficiency, by viral infection, or inherited defect. Occurs in several breeds of dogs including Samoyeds, Dalmatians, Chow Chows, Weimaraners, Bernese mountain dogs, English springer spaniels, in all of which it is inherited as an X-linked trait. See also hypomyelinogenesis congenita (calves) and congenital tremor syndrome (piglets).