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hypomyelination

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hy·po·my·e·li·na·tion (hp-m-l-nshn)
n.
Defective formation of myelin in the spinal cord and brain. Also called hypomyelinogenesis.

hypomyelination
abnormally reduced amount of myelin in nervous tissue.


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We are the parents of twin boys who were born developmentally delayed, with hypotonia and hypomyelination of their brains.
The Company has demonstrated that, when transplanted into an animal model of hypomyelination (shiverer mouse), HuCNS-SC cells engraft and differentiate into mature, specialized cells called oligodendrocytes, and form myelin sheaths around host nerve fibers.
The Company has demonstrated that, when transplanted into an animal model of hypomyelination (shiverer mouse), HuCNS-SC cells engraft and differentiate into mature oligodendrocytes and form myelin sheaths around host nerve fibers.
 
 
 
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