hypomagnesemia


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hypomagnesemia

 [hi″po-mag″nĕ-se´me-ah]
abnormally low magnesium content of the blood, manifested chiefly by neuromuscular hyperirritability. See table of Electrolyte Imbalances at electrolyte.

hy·po·mag·ne·se·mi·a

(hī'pō-mag'nē-sē'mē-ă),
Subnormal blood serum concentration of magnesium; may cause convulsions and concurrent hypocalcemia.

hypomagnesemia

/hy·po·mag·ne·se·mia/ (-mag″nes-ēm´e-ah) abnormally low magnesium content of the blood.

hypomagnesemia

[hī′pōmag′nisē′mē·ə]
an abnormally low concentration of magnesium in the blood plasma, which causes nausea, vomiting, muscle weakness, tremors, tetany, and lethargy. Tachycardia and arrhythmia may also occur. Mild hypomagnesemia is usually the result of inadequate absorption of magnesium in the kidney or intestine, although it is also seen after prolonged parenteral feeding and during lactation. A more severe form is associated with malabsorption syndrome, protein malnutrition, and parathyroid disease. Magnesium salts to correct the deficiency may be given orally or intravenously.

hypomagnesemia

Low blood magnesium, magnesium deficiency Metabolism A serum magnesium ≤ 1.5 mg/dL, often manifest by muscular hyperirritability Etiology Alcohol abuse, burns, dehydration, DKA, diarrhea, ↑ Ca2+, ↑ aldosterone, ↓ K+, ↓ PTH, post-bowel resection, malabsorption, malnutrition, pancreatitis, renal insufficiency, therapy with amphotericin B, calcium gluconate, diuretics, insulin, neomycin Clinical Cramping, ↑ tendon reflexes, tremors. See Magnesium.

hy·po·mag·ne·se·mi·a

(hī'pō-mag'nĕ-sē'mē-ă)
Deficiency of magnesium in blood; may be caused by chronic alcoholism, dehydration, diabetic acidosis, and chronic diarrhea, malabsorption syndrome, postoperative complication of bowel surgery, prolonged nasogastric suction, prolonged diuretic therapy, or starvation. Signs include arrhythmias, neuromuscular irritability, leg cramps, mood changes, confusion, hallucinations, or seizures.
Synonym(s): hypomagnesaemia.

Hypomagnesemia

An abnormally low concentration of magnesium in the blood.
Mentioned in: Magnesium Imbalance

hy·po·mag·ne·se·mi·a

(hī'pō-mag'nĕ-sē'mē-ă)
Subnormal blood serum concentration of magnesium; may cause convulsions and concurrent hypocalcemia.
Synonym(s): hypomagnesaemia.

hypomagnesemia (hī´pōmag´nəs-ē´mēə),

n a deficiency of magnesium in the blood serum (normal values range from 1.5 to 2.5 mEq/L). It may be associated with chronic alcoholism, starvation, and prolonged diuresis in congestive heart failure. Manifestations include muscular twitching, convulsions, and coma.

hypomagnesemia

abnormally low magnesium content of the blood, manifested clinically by neuromuscular excitability.
References in periodicals archive ?
Electrolyte abnormalities (all grades; grade 3 or 4) according to laboratory assessment at an incidence rate of >10% and a >2% difference between arms in patients receiving Portrazza plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone in study 1 included hypomagnesemia (83% vs 70%; 20% vs 7%), hypokalemia (28% vs 18%; 5% vs 3%), hypocalcemia (45% vs 30%; 6% vs 2%), albumin corrected hypocalcemia (36% vs 23%; 4% vs 2%), and hypophosphatemia (31% vs 23%; 8% vs 6%).
Summary of patient characteristics Patient 1 2 Age (years) 38 74 Gender M F QT-prolonging Sotalol Ondansetron medications Citalopram Bradycardia + + Hypokalemia 0 + Hypomagnesemia 0 + QTc interval (msec) 559 610 Suspected latent congenital long QT 0 + syndrome Torsade de pointes + + Ventricular + 0 fibrillation Treatment Magnesium + + Potassium 0 + Pacing + + Patient 3 4 Age (years) 89 42 Gender F F QT-prolonging Quinidine Amitriptyline medications Haloperidol Bradycardia 0 0 Hypokalemia + + Hypomagnesemia 0 + QTc interval (msec) 550 610 Suspected latent congenital long QT 0 0 syndrome Torsade de pointes + + Ventricular 0 0 fibrillation Treatment Magnesium 0 + Potassium + + Pacing 0 0 Table 2.
In such patients documented with hypomagnesemia, oral magnesium chloride of dependable potency and bioavailability should be administered until such time as the serum magnesium level is normalized or the condition producing the hypomagnesemia is reversed.
treated patients included rash/acneiform dermatitis (26% vs 1%), diarrhea (23% vs 12%), dehydration (16% vs 5%; primarily occurring in patients with diarrhea), hypokalemia (10% vs 4%), stomatitis/mucositis (4% vs < 1%), and hypomagnesemia (4% vs 0).
Hypomagnesemia is a significant predictor of cardiovascular and non-cardiovascular mortality in patients undergoing hemodialysis.
Since gastric acid does not appear to be essential for the absorption of magnesium, Hypomagnesemia induced by PPIs may be due to some mechanism other than the inhibition of gastric acid secretion.
The most common adverse events of Vectibix are skin rash with variable presentations, hypomagnesemia, paronychia, fatigue, abdominal pain, nausea, and diarrhea, including diarrhea resulting in dehydration.
The symptoms are very similar to those of parturient paresis ("milk fever") seen prior to lambing, hypomagnesemia ("staggers") and listeriosis.
Four of the hypokalemic patients had hypomagnesemia.
Chapter 191, Disorders of Magnesium Metabolism: Hypomagnesemia is fairly well covered.