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hypokalemic

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hypokalemic /hy·po·ka·le·mic/ (-kah-lēm´ik)
1. pertaining to or characterized by hypokalemia.
2. an agent that lowers blood potassium levels.

hypokalemic [hi″po-kah-le´mik]
1. pertaining to or characterized by hypokalemia.
2. an agent that so acts.

hypokalemic
1. pertaining to or characterized by hypokalemia.
2. an agent that lowers blood potassium levels.

feline hypokalemic polymyopathy
seen in cats with severe potassium depletion, usually caused by renal dysfunction and excessive urinary potassium losses. There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation.
Enlarge picture
Cervical ventroflexion in a cat with hypokalemic polymyopathy. By permission from Ettinger SJ, Feldman E, Textbook of Veterinary Internal Medicine, Saunders, 2004
hypokalemic nephropathy
chronic loss of potassium due to alimentary tract disease can cause vacuolar degeneration of renal tubular epithelium.


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Approximately 14% of outpatients are mildly hypokalemic, with approximately 80% of patients who receive diuretics become hypokalemic.
The most common side effect is hypokalemic hypertension, which is secondary to a block of 11beta-hydroxysteroid dehydrogenase type 2 at the level of the kidney, leading to an enhanced mineralocorticoid effect of cortisol.
Interactions Antihypertensives, diuretics: May increase hypokalemic effects of some diuretics.
 
 
 
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