Three patients had tuberculous meningitis (Figure 3); all of whom had presented with altered behavior and were diagnosed based on CSF pleocytosis, elevated protein count, and
hypoglycorrhachia, and all of whom showed clinical improvement with anti-tuberculous treatment.
15] Consistent CSF findings with acute bacterial meningitis include a polymorphonuclear pleocytosis,
hypoglycorrhachia and a raised CSF protein level.
017) and for those with hypoglycorrhachia (CSF glucose <45 mg/dL; p = 0.
Patients with a higher level of CSF pleocytosis, hypoglycorrhachia, and lymphocytic pleocytosis >50% were less likely to get tested for WNV.
5) Pleural/ascitic fluid analysis showing evidence of lymphocytic exudative effusion and CSF showing lymphocytic pleocytosis with
hypoglycorrhachia (low CSF glucose).
Thus, impairment of GLUT-1 results in a low glucose concentration in the CSF and causes
hypoglycorrhachia with clinical symptoms like seizures, mental retardation, and compromised brain development in children.
While
hypoglycorrhachia is seen rarely with enterovirus (as low as 10 mg/dL), low CSF glucose values are usually due to bacterial or tuberculous meningitis.
Diagnosis of neurocysticercosis CSF analysis *
Hypoglycorrhachia.
In view of Bell's palsy, meningeal symptoms, thoracic sensory level, areflexic flaccid paralysis, pleocytosis with neutrophilic predominance,
hypoglycorrhachia, and elevated protein in CSF, CMV infection in nervous system (specifically PRAM) was considered and intravenous ganciclovir was started.
CSF analysis indicated
hypoglycorrhachia, elevated protein level, and neutrophilic pleocytosis.
