hypoganglionosis

hypoganglionosis /hy·po·gan·gli·o·no·sis/ (-gang?gle-on-o´sis) lessened number of myenteric ganglion cells in the distal large bowel, with constipation; a congenital type of megacolon.

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hy·po·gan·gli·on·o·sis (hp-gnggl--nss)

n.

A reduction in the number of ganglionic nerve cells, especially of the ganglia of the myenteric plexus.

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hypogangliosis, hypoganglionosis

deficiency in the number of myenteric ganglion cells, usually in the colon leading to the development of megacolon. See also aganglionosis.

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Clydesdale myenteric hypogangliosis

megacolon develops at about 4-9 months old. Possibly an inherited trait.