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hypofibrinogenemia

   Also found in: Encyclopedia 0.01 sec.
hypofibrinogenemia /hy·po·fi·brin·o·gen·emia/ (-fi-brin″o-jĕ-ne´me-ah) deficiency of fibrinogen in the blood.
hy·po·fi·brin·o·ge·ne·mi·a (hp-f-brn-j-nm-)
n.
Abnormally low levels of serum fibrinogen.

hypofibrinogenemia
[-fī′brinōjənē′mē·ə]
Etymology: Gk, hypo + L, fibra, fiber; Gk, genein, to produce, haima, blood
a deficiency of fibrinogen, a blood clotting factor, in the blood. The condition may result from DIC as a complication of abruptio placentae. Also spelled hypofibrinogenaemia.

hypofibrinogenemia [hi″po-fi-brin″o-jĕ-ne´me-ah]
deficiency of fibrinogen in the blood; called also fibrinogenopenia. See also afibrinogenemia.

hypofibrinogenemia (hī´pōfīb-rin´ōjnē´mē),
n a reduction of fibrinogen in the blood. Excessive bleeding may occur following trauma. The deficiency of fibrinogen may be congenital or may result from faulty synthesis associated with liver disease and defibrinogenation resulting from disorders of pregnancy involving the placenta and amniotic fluid. The normal range is 200 to 600 mg/100 ml of plasma. Clot-ting deficiencies do not occur until the concentration falls below 75 mg/100 ml.

hypofibrinogenemia
deficiency of fibrinogen in the blood. Has been reported as an inherited defect in St. Bernard dogs; is acquired in liver disease and as a sequel of disseminated intravascular coagulation.

hypofibrinogenemia
↓ Fibrinogen in circulation. See Congenital afibrionogenemia.


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Patients with a history of afibrinogenemia, dysfibrinogenemia, or hypofibrinogenemia were excluded from this study.
45) Fibrinogen Polymorphisms Fibrinogen mutations leading to hypofibrinogenemia or dysfibrinogenemia are usually clinically silent or associated with a bleeding diathesis.
The Company's goal is to rapidly defibrinogenate the patient with a single dose of Viprinex, yet prevent prolonged hypofibrinogenemia with no multiple-day treatments and no titrations towards an optimal fibrinogen level.
 
 
 
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