12] or folic acid, or marked hypocellularity
of the BM as well as patients on oral iron therapy were excluded because these conditions can influence sTfR concentrations irrespective of iron status (9).
Following treatment, GISTs usually demonstrate hypocellularity
and prominent stromal changes in the form of sclerosis, calcifications, myxoid change, and necrosis (Figure 7).
1985) results in hypocellularity
, atrophy, and apoptosis in the thymus; however, the putative chemical mechanisms of action and cellular targets differ (Luebke et al.
The sections showed marked hypocellularity
but did not show any evidence of acute lymphoblastic leukemia.
We could not make this cytologic diagnosis because of the hypocellularity
of the specimen, which was mainly blood elements, and the inability to immunophenotype the few spindle cells that we detected (Figure 3, b).
A toxic effect on the bone marrow cannot be completely ruled out, however, since bone marrow hypocellularity
and increased bone marrow fat have been observed in animals.
22) However, given the extreme hypocellularity
of some well-differentiated mucinous adenocarcinomas, there may remain a small concern about the possibility that the malignant epithelia may have been missed, especially if the specimen was not submitted in its entirety for histologic examination.
Also, like glomangiopericytoma, there may be zones of hypocellularity
and hypercellularity with variable vasculature composed of staghorn-type and capillary-sized vessels.
The types of treatment effects that have been seen are hypocellularity
, myxoid stroma, fibrosis, and necrosis.