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hyperviscosity

   Also found in: Wikipedia 0.04 sec.
hyperviscosity /hy·per·vis·cos·i·ty/ (-vis-kos´ĭ-te) excessive viscosity, as of the blood.
Hyperviscosity
Thick, viscous blood, caused by the accumulation of large proteins, such as immunoglobulins, in the serum.

hyperviscosity
[-viskos′itē]
Etymology: Gk, hyper, excess; L, viscosus, sticky
extreme viscosity or thickness of fluid.

hyperviscosity
excessive viscosity, as of the blood.

hyperviscosity syndrome
increased viscosity of the blood occurs with IgM and IgA myelomas because of the high levels of macroglobulins; causes increased resistance to blood, hypoxia, organ failure, retinal lesions, abnormalities in platelet function, coagulation defects and cardiac failure.


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Patients may also present with lymphadenopathy, splenomegaly, hyperviscosity syndrome, cryoglobulinemia, peripheral neuropathy, cold agglutinin hemolysis, autoimmune thrombocytopenia, von Willebrand's disease and, in rare cases, amyloidosis.
Hypertension and hyperviscosity (hematocrit over 55%) of the blood are two potentially life-threatening adverse effects.
Patients at risk may include those with a history of atherosclerosis, multiple cardiovascular risk factors, advanced age, impaired cardiac output, and/or known or suspected hyperviscosity.
 
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