hyperviscosity


Also found in: Dictionary, Wikipedia.

hyperviscosity

 [hi″per-vis-kos´ĭ-te]
excessive viscosity, as of the blood.
hyperviscosity syndrome any of various syndromes associated with increased viscosity of the blood. One type is due to serum hyperviscosity and is characterized by spontaneous bleeding with neurologic and ocular disorders. Another type is characterized by polycythemia with retarded blood flow, organ congestion, reduced capillary perfusion, and increased cardiac effort. A third group includes conditions in which the deformability of erythrocytes is impaired, such as sickle cell anemia.

hyperviscosity

/hy·per·vis·cos·i·ty/ (-vis-kos´ĭ-te) excessive viscosity, as of the blood.

hyperviscosity

[-viskos′itē]
Etymology: Gk, hyper, excess; L, viscosus, sticky
extreme viscosity or thickness of fluid.

Hyperviscosity

Thick, viscous blood, caused by the accumulation of large proteins, such as immunoglobulins, in the serum.

hyperviscosity

excessive viscosity, as of the blood.

hyperviscosity syndrome
increased viscosity of the blood occurs with IgM and IgA myelomas because of the high levels of macroglobulins; causes increased resistance to blood, hypoxia, organ failure, retinal lesions, abnormalities in platelet function, coagulation defects and cardiac failure.
References in periodicals archive ?
Many patients produce monoclonal IgM, which may cause hyperviscosity syndrome, or type I or II cryoglobulinemia, which may lead to Raynaud syndrome, vasculitis, cold agglutinin hemolytic anemia, peripheral neuropathy, or immune complex disease (23,24).
Serum viscosity and hyperviscosity syndrome in IgG multiple myeloma-the relationship to Sia test and to concentration of M component.
WM can result in enlargement of the liver and spleen due to anemia and large amounts of immunoglobulin M can lead to hyperviscosity syndrome, in which the blood becomes abnormally thick.
The frequent association of this tumor with hyperviscosity symptoms due to the presence of monoclonal serum gammopathy, usually of the immunoglobulin (Ig) M type, is clinically important.
Factors involved in the biochemical etiology of human seminal plasma hyperviscosity.
Lymphoplasmacytic lymphoma (LPL) is a neoplasm of small B lymphocytes, plasmacytoid lymphocytes, and plasma cells, usually lacking CD5, and which has a serum monoclonal protein that may be associated with hyperviscosity and cryoglobulinemia.
Relative contraindications include sleep apnea, the metabolic syndrome, hyperviscosity states, and severe benign prostatic hypertrophy with intolerable lower urinary tract symptoms, Dr.
IVIG THERAPY RESULTS IN POSTINFUSIONAL HYPERVISCOSITY AND PSEUDOHYPONATREMIA ATTRIBUTABLE TO HYPERPROTEINEMIA.
Hematological abnormalities such as polycythemia, sickle-cell disease, and hyperviscosity syndromes can also lead to strokes.
Patients at risk may include those with a history of atherosclerosis, multiple cardiovascular risk factors, advanced age, impaired cardiac output, and/or known or suspected hyperviscosity, hypercoagulable disorders, and prolonged periods of immobilization.
Moreover, pharmaceutical preparations based on HL have recently been used for the treatment of MI (Wang et al 1998) and blood hyperviscosity (Zou et al.