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hypervariable region

   Also found in: Acronyms, Wikipedia 0.01 sec.
hypervariable region
regions present on light and heavy chains of immunoglobulins where most of the variation in amino acid sequences occurs. These are also sites of antigen binding.


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To amplify just the msp2/p44 gene in the expression site and to determine hypervariable region sequences, we used AB1221 and AB1266 (5'-GAAGAAGAGATTGGACTTTTGATCTGTC-3') or AB1221 and AB1267 (5'-GAGGAAGAGATTGGA CTTTTGAGCTGTC-3').
Cigarette smoking raised the risk for RA, but only in patients who did not carry the HLA-DRB1 alleles encoding a common "shared" epitope sequence in the third hypervariable region of the DRB1 chain.
This portion of the mtDNA control region is generally referred to as the hypervariable region I (HVR1).
 
 
 
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