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hypervariable region

   Also found in: Wikipedia 0.04 sec.
hypervariable region
regions present on light and heavy chains of immunoglobulins where most of the variation in amino acid sequences occurs. These are also sites of antigen binding.

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This portion of the mtDNA control region is generally referred to as the hypervariable region I (HVR1).
The complete genomes of the 25 DENV-1 strains analyzed showed high levels of nucleotide sequence identity in the 3' NCR, except for a small region of 50 nt immediately after the ORF, which is the hypervariable region.
For instance, each hypervariable region seems to be limited in its "choice' of structural conformation, according to Lesk.
 
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